Scientists Discover Hormone Blocks Pot "High"

Scientists Discover Hormone Blocks Pot "High"

Posted: Updated:
 French researchers have discovered that a naturally occurring hormone acts as a defense in the brain against the psychoactive effects of marijuana consumption.

The hormone, pregnenolone reduces the activity of a brain molecule that acts as a cannabinoid receptor.
 
Researches think the discovery could help people with addictions to marijuana, as well as allowing people to take medical marijuana without the behavioral effects.
 
The study was published in the journal Science.
 
About 147 million people globally – or about 2.5 percent of the population – use cannabis, according to the World Health Organization.

While cannabis products can alleviate symptoms of depression, glaucoma, spasms, and nausea associated with cancer and AIDS, they are also known to impair brain development, memory and lung function, and some say they can lead to addiction.

Researchers discovered the previously unknown role of pregnenolone when they administered high doses of cannabis to lab rats, on the order of three to 10 times more than the typical human marijuana smoker might be exposed to, Piazza told AFP.

The high doses of cannabis raised the brain's level of pregnenolone, which blocked the harmful effects of THC on the brain.

They also did tests in the lab on human cell lines – not human patients – that showed a similar blocking effect.

"We hope to be able to start clinical trials in people in a year to a year and a half," Piazza told AFP.

  • Share ThisMore>>

  • Venice Lightning Strike Survivor Meets His Rescuers

    Venice Lightning Strike Survivor Meets His Rescuers

    Friday, August 29 2014 12:48 PM EDT2014-08-29 16:48:58 GMT
    A month and a day has passed since the fatal lightning strike suddenly hit the shore off Venice Beach, hospitalizing about a dozen people. One of the most critically injured patients was reunited with his rescuers by the Venice Pier Thursday.
    A month and a day has passed since the fatal lightning strike suddenly hit the shore off Venice Beach, hospitalizing about a dozen people. One of the most critically injured patients was reunited with his rescuers by the Venice Pier Thursday.
  • National Dog Day: Send Us Your Pup Pics

    National Dog Day: Send Us Your Pup Pics

    Tuesday, August 26 2014 7:17 PM EDT2014-08-26 23:17:59 GMT
    The purpose of the holiday is to show appreciation for the millions of the dogs in the US that keep us safe and bring us comfort and companionship.
    The purpose of the holiday is to show appreciation for the millions of the dogs in the US that keep us safe and bring us comfort and companionship.
  • myFOX Tech

    Review: Microsoft Surface Pro 3- The Future of Laptops, NOW!

    Review: Microsoft Surface Pro 3- The Future of Laptops, NOW!

    Tuesday, August 26 2014 12:14 PM EDT2014-08-26 16:14:57 GMT
    It's no secret that Microsoft has struggled in the hardware department so I can't say whether the Surface Pro 3 will be the hero Microsoft needs but I can say it is the modern computing experience users deserve. I love it and think you should too! Read on to find out why.
    It's no secret that Microsoft has struggled in the hardware department so I can't say whether the Surface Pro 3 will be the hero Microsoft needs but I can say it is the modern computing experience users deserve. I love it and think you should too! Read on to find out why.
Powered by WorldNow
Didn't find what you were looking for?
All content © Copyright 2000 - 2014 Fox Television Stations, Inc. and Worldnow. All Rights Reserved.
Privacy Policy | New Terms of Service What's new | Ad Choices